Precision Chemistry for
Life-Changing Therapeutics.
TADEM’S THERAPEUTICS delivers high-purity active pharmaceutical ingredients, complex chemical intermediates, and custom CDMO synthesis with backward integration across our Bengaluru and Hyderabad hubs.
Rooted in Science. Dedicated to Global Healthcare.
Bridging discovery chemistry and commercial cGMP manufacturing through backward integration and sustainable processes.
Grounded in Science, Advancing Global Health
TADEM’S THERAPEUTICS AND PHARMA SOLUTIONS PRIVATE LIMITED is a research-led pharmaceutical manufacturing and CDMO enterprise. We specialize in complex chemical synthesis, route scouting, and the large-scale production of high-purity active substances and advanced intermediates.
Operating dual specialized hubs in Bengaluru (Corporate & Commercial HQ) and Hyderabad (R&D & Process Chemistry Hub), our technical infrastructure bridges benchtop discovery and commercial multi-ton cGMP production. We supply regulated healthcare markets worldwide with an uncompromised commitment to quality, patient safety, and data governance.
Commercial Active Ingredients & Intermediates
High-purity active pharmaceutical ingredients and therapeutic molecules manufactured to stringent USP, Ph. Eur., and IP pharmacopeial standards.
Cardiovascular
Anti-arrhythmics, direct thrombin inhibitors, and anti-coagulants engineered to global compendial monographs.
- Verapamil HCl USP / Ph. Eur.
- Dabigatran Ph. Eur. Grade
- Flecainide USP Standard
CNS & Neurology
Anti-epileptics, atypical antipsychotics, and neuropathic therapeutics manufactured under cGMP validation.
- Levetiracetam USP / EP / IP
- Clozapine USP Standard
- Pregabalin Ph. Eur. Grade
Anti-Infectives & Antivirals
Synthetic nucleoside analogues, viral inhibitors, and broad-spectrum agents with complete traceability.
- Valacyclovir USP Standard
- Acyclovir Ph. Eur. / BP
- Dolutegravir WHO-PQ Ready
Metabolic & Diabetes
SGLT-2 inhibitors, glycemic management, and thyroid hormone therapeutics with robust supply chains.
- Dapagliflozin USDMF Available
- Levothyroxine USP / EP Grade
- Empagliflozin CEP Ready
Oncology Care
Targeted small molecule kinase inhibitors and supportive therapeutic active substances.
- Imatinib Mesylate Ph. Eur. / USP
- Erlotinib USP Standard
- Ondansetron USP / EP / IP
Gastrointestinal
Proton pump inhibitors and gastro-protective molecules with enantiomeric purity controls.
- Esomeprazole USP / Ph. Eur.
- Pantoprazole Ph. Eur. Grade
- Aceclofenac IP / BP Standard
End-to-End Process Chemistry & Scale-Up
Accelerating novel chemical entities from laboratory route scouting to commercial multi-ton batch manufacture with dedicated R&D teams and backward-integrated synthesis.
Phase-Gated CDMO Execution
Our Hyderabad R&D hub specializes in high-barrier synthetic pathways with dedicated project management and open-door scientific communication under strict CDA/NDA agreements.
Route Scouting & PoC
Gram Scale (1g – 50g)Non-infringing green synthetic pathways, green solvent selection, and milligram-to-gram proof of concept.
Process DoE & Optimization
Kilo Scale (1kg – 10kg)Design of Experiments, parameter optimization, impurity profiling, and stoichiometric yield enhancement.
Kilo-Lab & Safety Screening
Pilot Scale (25kg – 100kg)Reaction calorimetry (RC1/DSC), process hazard analysis, and pilot-scale demonstration batches.
Commercial cGMP Synthesis
Commercial Multi-TonMulti-ton commercial batch manufacture with complete eCTD Type II DMF and CEP regulatory filings.
Core Chemical Reaction Platforms
Specialized reaction capabilities engineered for high-barrier pathways and demanding molecular architectures.
Cryogenic & Low-Temp Synthesis
Precision organolithium chemistry, stereoselective C-C bond formations, selective boronic acid coupling, and handling of pyrophoric reagents.
High-Pressure Catalytic Hydrogenation
Heterogeneous and homogeneous catalytic reductions using Pd/C, Pt/C, and Raney Nickel with rigorous safety protocols and automated pressure control.
Chiral Synthesis & Resolution
Classic diastereomeric salt resolution, dynamic kinetic resolution (DKR), and asymmetric organocatalysis delivering high optical purities.
Complex Heterocycles & Multi-Step
Specialized synthesis of fused heterocycles including substituted indoles, pyridines, piperazines, pyrimidines, and advanced intermediate building blocks.
One Quality Standard for All Markets
Impeccable regulatory track record with all molecules engineered to international pharmacopeias.
21 CFR Part 210/211 cGMP compliance with complete eCTD Type II Drug Master File (USDMF) submissions.
Certificates of Suitability (CEP) demonstrating full compliance with European Pharmacopoeia (Ph. Eur.) monographs.
World Health Organization Prequalification standards ensuring life-saving anti-infective therapeutic supply.
Japanese Pharmacopoeia (JP) compliance and Foreign Manufacturer Accreditation (FMA) standard procedures.
Regulatory dossier clearance and GMP audit compliance for high-demand molecules across emerging markets.
Schedule M cGMP manufacturing licenses and written confirmation for European and international bulk chemical exports.
21 CFR Part 210/211 cGMP compliance with complete eCTD Type II Drug Master File (USDMF) submissions.
Certificates of Suitability (CEP) demonstrating full compliance with European Pharmacopoeia (Ph. Eur.) monographs.
World Health Organization Prequalification standards ensuring life-saving anti-infective therapeutic supply.
Japanese Pharmacopoeia (JP) compliance and Foreign Manufacturer Accreditation (FMA) standard procedures.
Regulatory dossier clearance and GMP audit compliance for high-demand molecules across emerging markets.
Schedule M cGMP manufacturing licenses and written confirmation for European and international bulk chemical exports.